Cognitive and Functional Outcomes in Adults with Moyamoya Post-Revascularization
A 1991-2021 Analysis
DOI:
https://doi.org/10.47611/jsrhs.v14i1.8747Keywords:
Moyamoya disease, revascularization, cerebrovascular reactivity, cognitive outcomes, ischemic stroke, hemorrhagic stroke, cerebral perfusion, posterior cerebral artery involvement, hyperperfusion, individualized surgical strategies, stroke prevention, neuropsychological assessment, angiographic scoring systemAbstract
Moyamoya disease is a rare and progressive cerebrovascular illness characterized by internal carotid artery stenosis and aberrant collateral vessel development. This syndrome raises the likelihood of ischemic and hemorrhagic strokes, which have serious consequences for patients' cognitive and functional capacities. Revascularization surgery is a common procedure; nevertheless, postoperative results vary, with some patients reporting increased cerebral perfusion and cognitive recovery and others enduring chronic or increasing deficits. This study combines data from ten peer-reviewed sources to look at the clinical and cognitive outcomes of revascularization surgery, identify predictors of postoperative success, and investigate the role of age, posterior cerebral artery involvement, and hyperperfusion in recovery (OpenAI, 2024).
Key findings show that revascularization decreases stroke risk and improves cerebrovascular reactivity, although cognitive outcomes are uneven, highlighting the multifaceted nature of recovery. Limitations in the examined studies, such as limited sample numbers and single-center designs, underscore the importance of future research with varied cohorts and longer follow-ups. This study adds to our understanding of specialized surgical methods, underlining the significance of targeted therapies for improving clinical and cognitive outcomes in Moyamoya disease patients. By addressing current gaps, the study lays the groundwork for better patient care and surgical techniques (OpenAI, 2024).
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