Ramifications of Sleep Deprivation and Stress on Juvenile Epilepsy

Authors

  • Sanjana Reka Obra D. Tompkins High School
  • Dr. John Gresham Obra D. Tompkins High School

DOI:

https://doi.org/10.47611/jsrhs.v12i4.5727

Keywords:

Sleep Deprivation, Stress, Epilepsy, Adolescents

Abstract

According to recent studies, there is a correlation between stress, sleep deprivation, and elevated levels of epileptic activity among the adult population. An increased presence of either sleep deprivation or stress within epileptic adults typically supports the correlation between stress and sleep deprivation and elevated levels of epileptic activity, showcasing them at an increased risk for experiencing an increase in epileptiform discharges, spike waves occurring in the form of a single discharge that is typically associated with epilepsy and seizures. Researchers have demonstrated that the presence of sleep deprivation and stress is a significant indicator for increased levels of epileptic activity in the adult population, however, they have yet to conclude whether the trend exists within adolescent populations diagnosed with epilepsy, specifically from the ages of 5 to 18. A qualitative study, an interview, and a questionnaire procedure with 47 respondents and 5 interviewees that were adolescents diagnosed with epilepsy and asked questions concerning three themes: (1) The presence of Stress in Juvenile Epilepsy, (2) REM Sleep Duration, (3) Academic and Societal Pressures. The results of the analyses concluded that I found the facilitation of increases in the epileptic activity to correlate with an increased presence of sleep deprivation and stress within adolescents with epilepsy, as it heightens the risk for seizures.

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References or Bibliography

Cobabe, M. M., Sessler, D. I., Nowacki, A. S., O’Rourke, C., Andrews, N., & Foldvary-Schaefer, N. (2015). Impact of sleep duration on seizure frequency in adults with epilepsy: A sleep diary study. Epilepsy & Behavior, 43, 143–148. https://doi.org/10.1016/j.yebeh.2014.12.012

Cohen, H. B., Duncan, R. F., & Dement, W. C. (1967). Sleep: The Effect of Electroconvulsive Shock in Cats Deprived of REM Sleep. Science, 156(3782), 1646–1648. http://www.jstor.org/stable/1721616

DeRoos, S. T., Chillag, K. L., Keeler, M., & Gilbert, D. L. (2009). Effects of Sleep Deprivation on the Pediatric Electroencephalogram. Pediatrics, 123(2), 703–708. https://doi.org/10.1542/peds.2008-0357

Espir, M., Richens, A., & Wood, C. B. S. (1985). Treatment For Teenagers With Epilepsy. British Medical Journal (Clinical Research Edition), 290(6479), 1433–1433. http://www.jstor.org/stable/29519187

Gilbert, D. L., DeRoos, S., & Bare, M. A. (2004). Does sleep or sleep deprivation increase epileptiform discharges in pediatric electroencephalograms? Pediatrics, 114(3), 658+. https://link.gale.com/apps/doc/A122418670/AONE?u=j101914012&sid=bookmark-AONE&xid=a1e7f970

Gustafsson, G., Broström, A., Ulander, M., Vrethem, M., & Svanborg, E. (2015). Occurrence of epileptiform discharges and sleep during EEG recordings in children after melatonin intake versus sleep-deprivation. Clinical Neurophysiology, 126(8), 1493–1497. https://doi.org/10.1016/j.clinph.2014.10.015

Halász, P., Filakovszky, J., Vargha, A., & Bagdy, G. (2002). Effect of sleep deprivation on spike-wave discharges in idiopathic generalized epilepsy: a 4×24 h continuous long term EEG monitoring study. Epilepsy Research, 51(1/2), 123. https://doi.org/10.1016/S0920-1211(02)00123-7

Maganti, R. K., & Jones, M. V. (2021). Untangling a Web: Basic Mechanisms of the Complex Interactions Between Sleep, Circadian Rhythms, and Epilepsy. Epilepsy Currents, 21(2), 105–110. https://doi.org/10.1177/1535759721989674

Maisuradze, L. M., Zhizhiashvili, L. V., Lomidze, G. V., & Kasradze, S. V. (2015). Daytime sleepiness and epilepsy: a pilot study. Neurophysiology, 47(6), 478+. https://link.gale.com/apps/doc/A451940778/AONE?u=j101914012&sid=bookmark-AONE&xid=a2f84f6

Malow B. A. (2004). Sleep deprivation and epilepsy. Epilepsy currents, 4(5), 193–195. https://doi.org/10.1111/j.1535-7597.2004.04509.x

Mekky, J. F., Elbhrawy, S. M., Boraey, M. F., & Omar, H. M. (2017). Sleep architecture in patients with Juvenile Myoclonic Epilepsy. Sleep Medicine, 38, 116–121. https://doi.org/10.1016/j.sleep.2017.02.01

Meritam, P., Gardella, E., Alving, J., Terney, D., Cacic Hribljan, M., & Beniczky, S. (2018). Diagnostic yield of standard-wake and sleep EEG recordings. Clinical Neurophysiology, 129(4), 713–716. https://doi.org/10.1016/j.clinph.2018.01.0

Milán-Tomás, Á., Conde-Blanco, E., Moreno-Rojas, A., & Hwang, P. (2016). 5. Sleep deprivation in the activation of interictal spikes and epileptic seizures. Clinical Neurophysiology, 127(9), e166. https://doi.org/10.1016/j.clinph.2016.05.266

Panayiotopoulos, C. P., Obeid, T., & Tahan, A. R. (1994). Juvenile myoclonic epilepsy: a 5‐year prospective study. Epilepsia, 35(2), 285-296.

Petruccelli, E., Lansdon, P., & Kitamoto, T. (2015). Exaggerated Nighttime Sleep and Defective Sleep Homeostasis in a Drosophila Knock-In Model of Human Epilepsy. PLoS ONE, 10(9). https://link.gale.com/apps/doc/A428322694/AONE?u=j101914012&sid=bookmark-AONE&xid=1654404

Xu L, Guo D, Liu Y, Qiao D, Ye J, Xue R. Juvenile myoclonic epilepsy and sleep. Epilepsy & Behavior. 2018;80:326-330. doi:10.1016/j.yebeh.2017.11.008

https://doi.org/10.1016/j.yebeh.2014.12.012

Published

11-30-2023

How to Cite

Reka, S., & Gresham, J. (2023). Ramifications of Sleep Deprivation and Stress on Juvenile Epilepsy. Journal of Student Research, 12(4). https://doi.org/10.47611/jsrhs.v12i4.5727

Issue

Section

AP Capstone™ Research