Galleria Mellonella as a model for drug screening of topical steroids against Malassezia Furfur

Alcazar-Fuoli, L., Buitrago, M., Gomez-Lopez, A., & Mellado, E. (2015). An alternative host model of a mixed fungal infection by azole susceptible and resistantaspergillusSPP strains. Virulence, 6(4), 376–384. https://doi.org/10.1080/21505594.2015.1025192

Alghoribi, M. F., Gibreel, T. M., Dodgson, A. R., Beatson, S. A., & Upton, M. (2014). Galleria mellonella infection model demonstrates high lethality of ST69 and ST127 uropathogenic E. coli. PloS one, 9(7), e101547. https://doi.org/10.1371/journal.pone.0101547

Asai, M., Li, Y., Khara, J. S., Robertson, B. D., Langford, P. R., & Newton, S. M. (2019). Galleria mellonella: An Infection Model for Screening Compounds Against the Mycobacterium tuberculosis Complex. Frontiers in microbiology, 10, 2630. https://doi.org/10.3389/fmicb.2019.02630

Beth Burgwyn Fuchs, Elizabeth O’Brien, Joseph B. El Khoury & Eleftherios Mylonakis (2010) Methods for using Galleria mellonella as a model host to study fungal pathogenesis, Virulence, 1:6, 475-482, DOI: 10.4161/viru.1.6.12985

Binder, U., Maurer, E., & Lass-Flörl, C. (2016). Galleria mellonella: An invertebrate model to study pathogenicity in correctly defined fungal species. Fungal biology, 120(2), 288–295. https://doi.org/10.1016/j.funbio.2015.06.002

Champion O. L., Wagley S., Titball R. W. (2016). Galleria Mellonella as a Model Host for Microbiological and Toxin Research. Virulence 7, 840–845. doi: 10.1080/21505594.2016.1203486

Chaves-Moreno, D., Wos-Oxley, M. L., Jáuregui, R., Medina, E., Oxley, A. P., Pieper, D. H. (2016). Exploring the Transcriptome of Staphylococcus Aureus in its Natural Niche. Sci. Rep. 6, 33174. doi: 10.1038/srep33174

Cotter, G., Doyle, S., & Kavanagh, K. (2000). Development of an insect model for the in vivo pathogenicity testing of yeasts. FEMS Immunology & Medical Microbiology, 27(2), 163–169. https://doi.org/10.1111/j.1574-695x.2000.tb01427.x

Cutuli, M. A., Petronio Petronio, G., Vergalito, F., Magnifico, I., Pietrangelo, L., Venditti, N., & Di Marco, R. (2019). Galleria mellonella as a consolidated in vivo model hosts: New developments in antibacterial strategies and novel drug testing. Virulence, 10(1), 527–541. https://doi.org/10.1080/21505594.2019.1621649

Desalermos, A., Tan, X., Rajamuthiah, R., Arvanitis, M., Wang, Y., Li, D., Kourkoumpetis, T. K., Fuchs, B. B., & Mylonakis, E. (2014). A multi-host approach for the systematic analysis of virulence factors in cryptococcus neoformans. Journal of Infectious Diseases, 211(2), 298–305. https://doi.org/10.1093/infdis/jiu441

Desbois, A. P., & Coote, P. J. (2011). Wax moth larva (Galleria mellonella): an in vivo model for assessing the efficacy of antistaphylococcal agents. The Journal of antimicrobial chemotherapy, 66(8), 1785–1790. https://doi.org/10.1093/jac/dkr198

Editorial, P. M. D. (2017, April 14). Fungal infection (malassezia pachydermatis) of the skin in dogs. PetMD. Retrieved September 27, 2021, from https://www.petmd.com/dog/conditions/skin/c_dg_malassezia_dermatitis.

Eisenhardt, M., Schlupp, P., Höfer, F., Schmidts, T., Hoffmann, D., Czermak, P., et al. (2019). The Therapeutic Potential of the Insect Metalloproteinase Inhibitor Against Infections Caused by Pseudomonas Aeruginosa. J. Pharm. Pharmacol. 71, 316–328. doi: 10.1111/jphp.13034

Fitts D. A. (2011). Ethics and animal numbers: informal analyses, uncertain sample sizes, inefficient replications, and type I errors. Journal of the American Association for Laboratory Animal Science : JAALAS, 50(4), 445–453.

Fuchs BB, Mylonakis E. Using non-mammalian hosts to study fungal virulence and host defense. Curr Opin Microbiol. 2006 Aug;9(4):346-51. doi: 10.1016/j.mib.2006.06.004. Epub 2006 Jun 30. PMID: 16814595.

Gao, Z., Perez-Perez, G. I., Chen, Y., & Blaser, M. J. (2010). Quantitation of major human cutaneous bacterial and fungal populations. Journal of clinical microbiology, 48(10), 3575–3581. https://doi.org/10.1128/JCM.00597-10

García-Lara J., Needham A. J., Foster S. J. (2005). Invertebrates as Animal Models for Staphylococcus Aureus Pathogenesis: A Window Into Host–Pathogen Interaction. FEMS Immunol. Med. Microbiol. 43, 311–323. doi: 10.1016/j.femsim.2004.11.003

Gomez-Lopez, A., Forastiero, A., Cendejas-Bueno, E., Gregson, L., Mellado, E., Howard, S. J., Livermore, J. L., Hope, W. W., & Cuenca-Estrella, M. (2014). An invertebrate model to evaluate virulence in aspergillus fumigatus: The role of Azole Resistance. Medical Mycology, 52(3), 311–319. https://doi.org/10.1093/mmy/myt022

Harding, C. R., Schroeder, G. N., Collins, J. W., & Frankel, G. (2013). Use of Galleria mellonella as a model organism to study Legionella pneumophila infection. Journal of visualized experiments : JoVE, (81), e50964. https://doi.org/10.3791/50964

Harding, C. R., Schroeder, G. N., Reynolds, S., Kosta, A., Collins, J. W., Mousnier, A., & Frankel, G. (2012). Legionella pneumophila pathogenesis in the Galleria mellonella infection model. Infection and immunity, 80(8), 2780–2790. https://doi.org/10.1128/IAI.00510-12

Hoffmann, J. The immune response of Drosophila. Nature 426, 33–38 (2003). https://doi.org/10.1038/nature02021

Hunter, T., & Hunter, C. T. (n.d.). Yeast dermatitis in dogs. vca_corporate. Retrieved September 27, 2021, from https://vcahospitals.com/know-your-pet/yeast-dermatitis-in-dogs.

James D Ellis, Jason R Graham & Ashley Mortensen (2013) Standard methods for wax moth research, Journal of Apicultural Research, 52:1, 1-17, DOI: 10.3896/IBRA.1.52.1.10

Jorjão, A. L., Oliveira, L. D., Scorzoni, L., Figueiredo-Godoi, L., Cristina A Prata, M., Jorge, A., & Junqueira, J. C. (2018). From moths to caterpillars: Ideal conditions for Galleria mellonella rearing for in vivo microbiological studies. Virulence, 9(1), 383–389. https://doi.org/10.1080/21505594.2017.1397871

Kaito, C., Murakami, K., Imai, L., & Furuta, K. (2020). Animal infection models using non-mammals. Microbiology and immunology, 64(9), 585–592. https://doi.org/10.1111/1348-0421.12834

Kwadha, C. A., Ong'amo, G. O., Ndegwa, P. N., Raina, S. K., & Fombong, A. T. (2017). The Biology and Control of the Greater Wax Moth, Galleria mellonella. Insects, 8(2), 61. https://doi.org/10.3390/insects8020061

Lavine, M. D., & Strand, M. R. (2002). Insect hemocytes and their role in immunity. Insect biochemistry and molecular biology, 32(10), 1295–1309. https://doi.org/10.1016/s0965-1748(02)00092-9

Lewis, A. J., Seymour, C. W., & Rosengart, M. R. (2016). Current Murine Models of Sepsis. Surgical Infections, 17(4), 385–393. https://doi.org/10.1089/sur.2016.021

Loh, J. M., Adenwalla, N., Wiles, S., & Proft, T. (2013). Galleria mellonella larvae as an infection model for group A streptococcus. Virulence, 4(5), 419–428. https://doi.org/10.4161/viru.24930

Maurer, E., Hörtnagl, C., Lackner, M., Grässle, D., Naschberger, V., Moser, P., Segal, E., Semis, M., Lass-Flörl, C., & Binder, U. (2018). Galleria mellonella as a model system to study virulence potential of mucormycetes and evaluation of antifungal treatment. Medical Mycology, 57(3), 351–362. https://doi.org/10.1093/mmy/myy042

Mowlds, P., & Kavanagh, K. (2007). Effect of pre-incubation temperature on susceptibility of galleria mellonella larvae to infection by candida albicans. Mycopathologia, 165(1), 5–12. https://doi.org/10.1007/s11046-007-9069-9

Mylonakis, E., Moreno, R., El Khoury, J. B., Idnurm, A., Heitman, J., Calderwood, S. B., Ausubel, F. M., & Diener, A. (2005). galleria mellonella as a model system to study cryptococcus neoformans pathogenesis. Infection and Immunity, 73(7), 3842–3850. https://doi.org/10.1128/iai.73.7.3842-3850.2005

Ménard, G., Rouillon, A., Cattoir, V., & Donnio, P. Y. (2021). Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future. Frontiers in cellular and infection microbiology, 11, 782733. https://doi.org/10.3389/fcimb.2021.782733

O'Callaghan D, Vergunst A. Non-mammalian animal models to study infectious disease: worms or fly fishing? Curr Opin Microbiol. 2010 Feb;13(1):79-85. doi: 10.1016/j.mib.2009.12.005. Epub 2010 Jan 4. PMID: 20045373.

Pereira M. F., Rossi C. C., da Silva G. C., Rosa J. N., Bazzolli D. M. S. (2020). Galleria Mellonella as an Infection Model: An in-Depth Look at Why it Works and Practical Considerations for Successful Application. Pathog. Dis. 78, ftaa056. doi: 10.1093/femspd/ftaa056

Pereira, T. C., de Barros, P. P., Fugisaki, L., Rossoni, R. D., Ribeiro, F. C., de Menezes, R. T., Junqueira, J. C., & Scorzoni, L. (2018). Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens. Journal of fungi (Basel, Switzerland), 4(4), 128. https://doi.org/10.3390/jof4040128

Peterson, R. T., Nass, R., Boyd, W. A., Freedman, J. H., Dong, K., & Narahashi, T. (2008). Use of non-mammalian alternative models for neurotoxicological study. Neurotoxicology, 29(3), 546–555. https://doi.org/10.1016/j.neuro.2008.04.006

Rice, Jennifer C., "Effects of "Lemongrass Factor" on Galleria Mellonella Hemocytes" (2021). MSU Graduate Theses. 3694.https://bearworks.missouristate.edu/theses/3694

Rowan, R., Moran, C., McCann, M., & Kavanagh, K. (2009). Use of Galleria mellonella larvae to evaluate the in vivo anti-fungal activity of [Ag2(mal)(phen)3]. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 22(3), 461–467. https://doi.org/10.1007/s10534-008-9182-3

Szafranska, A. K., Oxley, A. P. A., Chaves-Moreno, D., Horst, S. A., Roßlenbroich, S., Peters, G., et al. (2014). High-Resolution Transcriptomic Analysis of the Adaptive Response of Staphylococcus Aureus During Acute and Chronic Phases of Osteomyelitis. mBio 5, e01775–14. doi: 10.1128/mBio.01775-14

Torres, M., Pinzón, E. N., Rey, F. M., Martinez, H., Parra Giraldo, C. M., & Celis Ramírez, A. M. (2020). Galleria mellonella as a Novelty in vivo Model of Host-Pathogen Interaction for Malassezia furfur CBS 1878 and Malassezia pachydermatis CBS 1879. Frontiers in Cellular and Infection Microbiology, 10. https://doi.org/10.3389/fcimb.2020.00199

Trevijano-Contador, N., & Zaragoza, O. (2018). Immune Response of Galleria mellonella against Human Fungal Pathogens. Journal of fungi (Basel, Switzerland), 5(1), 3. https://doi.org/10.3390/jof5010003

Tsai, C. J., Loh, J. M., & Proft, T. (2016). Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing. Virulence, 7(3), 214–229. https://doi.org/10.1080/21505594.2015.1135289

Velegraki, A., Cafarchia, C., Gaitanis, G., Iatta, R., & Boekhout, T. (2015). Malassezia infections in humans and animals: pathophysiology, detection, and treatment. PLoS pathogens, 11(1), e1004523. https://doi.org/10.1371/journal.ppat.1004523

Wittwer, D., Franchini, A., Ottaviani, E., & Wiesner, A. (1999). Presence of IL-1- and TNF-like molecules in Galleria mellonella (Lepidoptera) haemocytes and in an insect cell line Fromestigmene acraea (Lepidoptera). Cytokine, 11(9), 637–642. https://doi.org/10.1006/cyto.1998.0481

Wojda, I., Staniec, B., Sułek, M., & Kordaczuk, J. (2020). The greater wax moth Galleria mellonella: biology and use in immune studies. Pathogens and disease, 78(9), ftaa057. https://doi.org/10.1093/femspd/ftaa057

Zhan L, Tang J, Sun M, Qin C. Animal Models for Tuberculosis in Translational and Precision Medicine. Front Microbiol. 2017 May 4;8:717. doi: 10.3389/fmicb.2017.00717. PMID: 28522990; PMCID: PMC5415616.